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Hydrocortisone sodium phosphate is the sodium phosphate ester of hydrocortisone, a water-soluble corticosteroid with glucocorticoid anti-inflammatory activity and a short duration of action. It is supplied as a solid research reagent for biochemical and pharmacological studies; consult the safety data sheet for handling and storage.
Water-soluble sodium phosphate ester of hydrocortisone.
Provides glucocorticoid anti-inflammatory activity with short duration of action.
High reported purity supports analytical and biological experiments.
Suitable for in vitro and in vivo research applications.
Packaged as a 25 mg solid for convenient small-scale use.
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Prednisone is a synthetic glucocorticoid which functions primarily as an agonist of the glucocorticoid receptor (GR) Upon binding to the GR prednisone induces receptor translocation into the nucleus initiating the regulation of gene expression involved in inflammation immune responses and cellular proliferation Due to its immunosuppressive mechanism prednisone is widely used as an experimental tool in biomedical studies exploring inflammatory diseases autoimmune conditions and immune signaling pathways Structurally prednisone is a corticosteroid derivative characterized by specific modifications that affect its pharmacodynamics and bioavailability In laboratory settings prednisone assists researchers in dissecting glucocorticoid-mediated physiological and molecular events evaluating receptor-ligand interactions and examining downstream signaling mechanisms in various cell-based assays and animal models
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Dexamethasone acetate (Decadron-LA) belongs to the class of long-acting glucocorticoids commonly used as a pharmaceutical ingredient in creams ointments microemulsions lotions aerosols etc.This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. for further information and support please go to the website of the issuing Pharmacopoeia.
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Glycocholic acid is a bile acid with anticancer activity, targeting against pump resistance-related and non-pump resistance-related pathways. It works by modulating P-gp and MRPs, and regulating apoptosis-related pathways when combined with anticancer drugs.
Increases cytotoxicity of epirubicin
Increases intracellular accumulation and absorption of epirubicin
Intensifies epirubicin-induced apoptosis
Reduces mRNA expression levels of human intestinal MDR1, MDR-associated protein (MRP)1, and MRP2
Downregulates the MDR1 promoter region
Suppresses mRNA expression of Bcl-2
Induces mRNA expression of Bax
Increases Bax-to-Bcl-2 ratio and mRNA levels of p53, caspase-9 and -3
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Glycocholic acid is a bile acid with anticancer activity, targeting pump resistance-related and non-pump resistance-related pathways. It is for research use only and not sold to patients.
Appearance: Solid
Color: White to off-white
Classification: Steroids
Initial source: Endogenous metabolite, human gut microbiota metabolites
Increases the cytotoxicity of epirubicin
Modulates P-gp and MRPs as well as regulating apoptosis-related pathways
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Glycocholic acid sodium is an orally active bile acid that exhibits anticancer activity by targeting both pump resistance-related and non-pump resistance-related pathways.
Orally active bile acid
Possesses anticancer activity
Targets pump resistance-related and non-pump resistance-related pathways
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Sodium glycocholate hydrate is a buffer commonly used in molecular biology and biochemical research. It provides precise pH control in various experimental settings and is intended for research use only.
Buffer commonly used in molecular biology and biochemical research
Provides precise pH control in various experimental settings
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